She has no significance.
1. It never actually involved Hillary Clinton
2. It was 20 years ago
Whether you agree with Hillary Clinton or not, you have no business bringing up the sex scandal of her husband as a means of devaluing her ability to lead.
Don't use it to discredit her, don't use it to insinuate that she's unable to lead, don't even joke about it. Feel free to take umbrage with her on any and all POLICY related issues your heart desires, but don't bring up a sex scandal. Please, show some decorum.
I really don't have much else to say on the subject because it's that simple.