"It's the oldest story in the world. One day you're seventeen and planning for someday. And then quietly, without you ever really noticing, someday is today. And then someday is yesterday. And this is your life." - Nathan Scott
"You can choose to blame your circumstances on fate, or bad luck, or bad choices, or you can fight back. Things aren’t always gonna be fair in the real world, that’s just the way it is. But for the most part you get what you give. Let me ask you all a question; what’s worse, not getting everything you wished for or getting it all and finding out it’s not enough? The rest of your life is being shaped right now with the dreams you chase, the choices you make, and the person you decide to be. The rest of your life is a long time and the rest of your life starts right now." -Haley James Scott
“People are gonna label you. It's how you overcome those labels. That's what matters." -Brooke Davis
“Sometimes, it’s easy to feel like you’re the only one in the world who’s struggling, who’s frustrated, or unsatisfied, or barely getting by. That feeling is a lie. And if you just hold on, just find the courage to face it all for another day, someone or something will find you and make it all okay, because we all need a little help sometimes, someone to help us hear the music in the world, to remind us that it won’t always be this way. That someone is out there, and that someone will find you.” -Lucas Scott
"At this moment, there are six billion, four hundred seventy million, eight hundred eighteen thousand, six hundred seventy one people in the world. Some are running scared. Some are coming home. Some tell lies to make it through the day. Others are just now facing the truth. Some are evil men, at war with good. And some are good, struggling with evil. Six billion people in the world, six billion souls. And sometimes all you need is one." -Peyton Sawyer
"It doesn’t matter how you plan it. It doesn’t matter how you envision it. Without even knowing it, sometimes life has a way of finding you with exactly what you need. Or exactly who you need." -Quinn James
"Sometimes I think that we waste our words and we waste our moments, and we don't take the time to say the things that are in our hearts when we have the chance." -Clay Evans
"That pain in your stomach, that pain in your heart, it goes away. That voice in your head thats saying there's no way out, it's wrong. Would you please, please just believe me? It gets better." -Keith Scott
"Happiness doesn't come cheap. Hell, if it did we'd all be smiling." -Dan Scott
"I feel like people get lost when they think of happiness as a destination. We're always thinking that someday we'll be happy, when we get that car, or that job, or that person in our lives that will fix everything. But happiness is a mood and it's a condition, not a destination. It's like being tired or hungry. It's not permanent. It comes and goes, and that's okay. And I feel like if people thought of it that way, they'd find happiness a lot more often." -Julian Baker
"All you can do is your best, OK?" -James Lucas Scott
"Because sometimes you have to step outside of the person you've been and remember the person you were meant to be. The person you wanted to be. The person you are." -Marvin 'Mouth' McFadden
"The important thing is not to be bitter over life’s disappointments. Learn to let go of the past, and recognize that everyday won’t be sunny. And when you find yourself lost in the darkness and despair, remember it’s only in the black of night you can see the stars, and those stars will lead you back home. So don’t be afraid to make mistakes, to stumble, to fall, because most of the time the greatest rewards come from doing the things that scare you the most. Maybe you’ll get everything you wish for. Maybe you’ll get more than you ever could have imagined. Who knows where life will take you. The road is long and in the end, the journey is the destination." -Whitey Durham
Always and forever... 
