Two People Have Now Been Effectively Cured Of HIV

A Second Person Has Achieved Long-Term Remission Of The HIV Virus

A second man has had long term remission of the HIV virus.

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Over a decade after the first man, known as the Berlin Patient, was declared HIV-free, another patient may also be cured. Though it's too early for scientists to say for sure, the London Patient has been in a long term remission for around 18 months without the help of medication. Both men were treated with a bone marrow transplant. However, these stem cells carried a rare mutation in the genes that affect the production of the CCR5 protein, which HIV viruses latch onto to enter the cell. The virus cannot latch onto the mutated version of the protein, thus blocking its entry into the cells.

With the transplant of these HIV resistant genes, the body effectively builds a new immune system free of the virus.

After the Berlin Patient went into remission, scientists tried and failed to replicate the cure and were unable to until the London Patient, whose HIV count has reduced into undetectable numbers. While this is extremely helpful, bone marrow transplants are not a viable option to cure all HIV infected people, as it is an extremely risky process and comes with many side effects. Even so, scientists are developing ways to extract bone marrow from HIV infected people, genetically modifying them to produce the same mutations on the CCR5 gene or the inability to express that gene at all, and then replacing it back into the patient so they can still build resistance without the negative effects of a bone marrow transplant. There have also been babies whose genomes have been edited to remove the CCR5 gene, allowing them to grow up resistant to HIV.

This does not eliminate the threat of the HIV virus, however.

There is another strand of the virus, called X4, that uses the CXCR4 protein to enter the cell. Even if the editing of the CCR5 allows immunity against one strand, it is possible for a person to be infected with the X4 strand of the virus. Despite this, immunization against one strand could save a countless number of lives, as well as the vaccine that is currently in the stages of development for HIV. Along with the London Patient, there are 37 other patients who have received bone marrow transplants, six of which from donors without the mutation.

Of these patients, number 19, known as the Dusseldorf Patient, has been off anti-HIV drugs for 4 months. It may not be a complete cure, but it is definitely a step in the right direction.

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To The Girl Struggling With Her Body Image

It's not about the size of your jeans, but the size of your heart, soul, and spirit.

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To the girl struggling with her body image,

You are more than the number on the scale. You are more than the number on your jeans and dresses. You are way more than the number of pounds you've gained or lost in whatever amount of time.

Weight is defined as the quantity of matter contained by a body or object. Weight does not define your self-worth, ambition or potential.

So many girls strive for validation through the various numbers associated with body image and it's really so sad seeing such beautiful, incredible women become discouraged over a few numbers that don't measure anything of true significance.

Yes, it is important to live a healthy lifestyle. Yes, it is important to take care of yourself. However, taking care of yourself includes your mental health as well. Neglecting either your mental or physical health will inflict problems on the other. It's very easy to get caught up in the idea that you're too heavy or too thin, which results in you possibly mistreating your body in some way.

Your body is your special, beautiful temple. It harbors all of your thoughts, feelings, characteristics, and ideas. Without it, you wouldn't be you. If you so wish to change it in a healthy way, then, by all means, go ahead. With that being said, don't make changes to impress or please someone else. You are the only person who is in charge of your body. No one else has the right to tell you whether or not your body is good enough. If you don't satisfy their standards, then you don't need that sort of negative influence in your life. That sort of manipulation and control is extremely unhealthy in its own regard.

Do not hold back on things you love or want to do because of how you interpret your body. You are enough. You are more than enough. You are more than your exterior. You are your inner being, your spirit. A smile and confidence are the most beautiful things you can wear.

It's not about the size of your jeans. It's about the size of your mind and heart. Embrace your body, observe and adore every curve, bone and stretch mark. Wear what makes you feel happy and comfortable in your own skin. Do your hair and makeup (or don't do either) to your heart's desire. Wear the crop top you've been eyeing up in that store window. Want a bikini body? Put a bikini on your body, simple.

So, as hard as it may seem sometimes, understand that the number on the scale doesn't measure the amount or significance of your contributions to this world. Just because that dress doesn't fit you like you had hoped doesn't mean that you're any less of a person.

Love your body, and your body will love you right back.

Cover Image Credit: Lauren Margliotti

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In Real Life, 'Plus Size' Means A Size 16 And Up, Not Just Women Who Are Size 8's With Big Breasts

The media needs to understand this, and give recognition to actual plus-size women.

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Recently, a British reality dating TV show called "Love Island" introduced that a plus-sized model would be in the season five lineup of contestants. This decision was made after the show was called out for not having enough diversity in its contestants. However, the internet was quick to point out that this "plus-size model" is not an accurate representation of the plus-size community.


@abidickson01 on twitter.com


Anna Vakili, plus-size model and "Love Island "Season 5 Contestant Yahoo UK News

It is so frustrating that the media picks and chooses women that are the "ideal" version of plus sized. In the fashion world, plus-size starts at size 8. EIGHT. In real life, plus-size women are women who are size 16 and up. Plunkett Research, a marketing research company, estimated in 2018 that 68% of women in America wear a size 16 to 18. This is a vast difference to what we are being told by the media. Just because a woman is curvy and has big breasts, does NOT mean that they are plus size. Marketing teams for television shows, magazines, and other forms of media need to realize that the industry's idea of plus size is not proportionate to reality.

I am all for inclusion, but I also recognize that in order for inclusion to actually happen, it needs to be accurate.

"Love Island" is not the only culprit of being unrealistic in woman's sizes, and I don't fully blame them for this choice. I think this is a perfect example of the unrealistic expectations that our society puts on women. When the media tells the world that expectations are vastly different from reality, it causes women to internalize that message and compare themselves to these unrealistic standards.

By bringing the truth to the public, it allows women to know that they should not compare themselves and feel bad about themselves. Everyone is beautiful. Picking and choosing the "ideal" woman or the "ideal" plus-size woman is completely deceitful. We as a society need to do better.

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