Starting in 2005, Shonda Rhimes created one of the longest running shows of all time, Grey's Anatomy. With 12 completed seasons and the beginning of the 13th starting, it has been an emotional roller coaster over the years. With the death of many beloved characters including George O'Malley, Lexie Grey, Mark Sloan, and the worst of all Derek Shephard and our other favorites leaving the show including Preston Burke, Izzie Stephens, Christina Yang, Addison Montgomery, and Callie Torres. After 11 years of the show and over 275 episodes, here are the most memorable, heartbreaking, engaging episodes of Grey's, so far.
1. "It's the end of the World"/ "As we know it"![]()

Season 2, episode 16/17
2. "Losing my religion" 
Season 2, episode 27
3. "Walk on water"/ "Drowning on dry land"/ "Some kind of miracle" 
Season 3, episode 15/16/17
4. "Now or Never"
5. "Sanctuary"/ "Death and all his friends"
Season 6, episode 23/24
6. "With you I'm born again" 
Season 7, episode 1
7. "Song beneath the song"
Season 7, episode 18
8. "Flight" 
Season 8, episode 24
9. "Seal our fate"/"I want you with me"
Season 10, episode 1/2































